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Infectious Disease & Antimicrobial Stewardship

Infectious Disease & Antimicrobial Stewardship

NAPPSA Resource Library

Infectious Disease & Antimicrobial Stewardship

Collection integrating infectious diseases, antimicrobial stewardship, vaccines, global public health, regulatory updates, clinical trials, and AJPPS research.

Featured AJPPS Research

Featured AJPPS infectious disease articles are added as they are curated. Browse the full journal on the AJPPS Journal page.

Latest Intelligence

For recent reporting, visit News & Updates. Check the original source and publication date.

WHO, CDC & FDA Updates

  • New WHO technical package to help countries improve health data for COVID-19 response and beyond
    on 10/10/2026 at 7:49 am

    Today, as part of its commitment to strengthening health information systems and improving health[1], especially in the context of the COVID-19 pandemic, WHO announced a new approach to improving access to life-saving data: the SCORE for Health Data Technical Package. The COVID-19 pandemic has highlighted the urgent need for timely and reliable data to drive strategic health action. Too many countries still lack both the infrastructure to routinely gather health data and the analytical capacity to use these data for effective health actions and emergency response. “Countries must be able to measure progress to make progress,” said WHO Director-General Dr Tedros Adhanom Ghebreyesus. “Particularly during COVID-19, reliable data is the best way to coordinate response efforts and improve health in all areas.” Accurate health data are necessary to understand specific country needs in order to improve health and save lives. Data also helps direct scarce resources to where they are needed most. The SCORE (Survey, Count, Optimize, Review, Enable) Technical Package aims to improve the availability of timely, reliable, validated, and comparable health data. For the first time in a single, harmonized package, it represents all the key elements for optimized health information system performance. Simply put, SCORE will help governments around the globe set benchmarks and improve standards in healthcare.In response to the challenges of data availability highlighted in the WHO World Health Statistics 2020 report, SCORE includes more than 90 universally-accepted tools and standards for health information systems strengthening. “Using data to inform public health priorities and strategies has never been more important,” said Dr Kelly Henning, Director of Public Health Programs at Bloomberg Philanthropies[2]. “The SCORE Technical Package provides country governments around the world with high-quality, essential technical guidance so that countries can strengthen their own data systems.” WHO is proud to partner with the Bloomberg Philanthropies Data for Health Initiative to deliver this timely resource to countries.  Below are some examples of how SCORE can improve individual lives and communities:The birth of a child is registered so they can access essential health services, attend school, and apply for a passport;A death is registered with cause-of-death accurately captured so that policy-makers have a better understanding of all-cause and COVID-specific mortality and associated risk factors and implement programs and policies to save lives;Health data are disaggregated by age, sex and cause of death to illustrate the root causes of health disparities and help direct resources to the most vulnerable groups such as those who do not speak the local language or face stigma and discrimination in their community; Health facilities have the capacity to regularly measure the quality of their services, workforce and patient data and can make a compelling case for increased funding to national and international stakeholders;Health data are integrated with other sectors so that social determinants of health such as pollution, sanitation and nutrition are addressed to reduce the overall burden of disease.The package's initial release includes two documents: SCORE Essential Interventions – including an overview of health information systems, underlying elements, and indicators to assess progress with sample actions; andSCORE Tools and Standards -- including resources to address critical health data gaps and strengthen country health data.“We must keep score to save lives. WHO is committed to working with countries and partners to rapidly scale up capacity for data collection and use in order to improve policy and performance,” added Dr Samira Asma, Assistant Director-General for Data, Analytics and Delivery for Impact at WHO. “We must act now to invest in statistical systems in countries, respond to this pandemic and meet the SDGs and the Triple Billion targets. Our window of opportunity is closing, and we cannot wait to address data gaps. Data use to address country needs has to be a priority today.”Country-owned, disaggregated data will be essential for more resilient and sustainable health systems going forward. COVID-19 is both a wake-up call and a stark reminder of the challenges we still have to address. But it is also an opportunity to build back better through solidarity, information-sharing and collaboration. SCORE is one example of how a collaborative approach can benefit countries by providing a common set of tools based on shared standards. This package is designed to be practical, actionable and flexible. We will only be successful in combatting COVID-19 if we work together.Future components of the SCORE Technical Package are due to be released later this year, including the SCORE Assessment Instrument and global, regional and country status reports.  Together, these will provide a complete package of information to plan and monitor progress against national and subnational priorities as well as global targets.-----[1] https://www.who.int/about/what-we-do/thirteenth-general-programme-of-work-2019---2023#:~:text=The%20Thirteenth%20General%20Programme%20of,health%20at%20the%20country%20leve[2] Bloomberg Philanthropies Data for Health Initiative provided funding to support the SCORE for Health Data Technical Package  

  • WHO statement on notification of withdrawal of the United States
    on 01/24/2026 at 8:09 pm

    WHO regrets the United States’ notification of withdrawal from WHO – a decision that makes both the United States and the world less safe. The notification of withdrawal raises issues that will be considered by the WHO Executive Board at its regular meeting starting on 2 February and by the World Health Assembly at its annual meeting in May 2026.

  • Timor-Leste certified malaria-free by WHO
    on 07/23/2025 at 10:07 am

    The World Health Organization (WHO) has certified Timor-Leste as malaria-free, a remarkable achievement for a country that prioritized the disease and embarked on a concerted, nation-wide response shortly after gaining independence in 2002.“WHO congratulates the people and government of Timor-Leste on this significant milestone,” said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. “Timor-Leste’s success proves that malaria can be stopped in its tracks when strong political will, smart interventions, sustained domestic and external investment and dedicated health workers unite.”With today’s announcement, a total of 47 countries and 1 territory have been certified as malaria-free by WHO. Timor-Leste is the third country to be certified in the WHO South-East Asia region, joining Maldives and Sri Lanka which were certified in 2015 and 2016 respectively.Certification of malaria elimination is granted by WHO when a country has proven, beyond reasonable doubt, that the chain of indigenous transmission has been interrupted nationwide for at least the previous three consecutive years.“We did it. Malaria has been one of our most relentless enemies – silent, persistent, and deadly. We lost too many lives to a disease that should be preventable. But our health workers never gave up, our communities held strong, and our partners, like WHO, walked beside us. From 223 000 cases to zero – this elimination honours every life lost and every life now saved. We must safeguard this victory with continued vigilance and community action to prevent malaria's re-entry,” said Dr Élia António de Araújo dos Reis Amaral, SH, Minister of Health, Government of Timor-Leste. A rapid shift from high burden country to malaria-freeSince gaining independence in 2002, Timor-Leste has made remarkable strides in the fight against malaria – reducing cases from a peak of more than 223 000 clinically diagnosed cases in 2006 to zero indigenous cases from 2021 onwards.Timor-Leste’s success in eliminating malaria was driven by the Ministry of Health’s swift action in 2003 to establish the National Malaria Programme, a dedicated programme for planning, implementing, and monitoring malaria control efforts nationwide. With only two full-time officers initially, the programme was able to lay the foundation for progress early on through strong technical leadership, managerial capacity and attention to detail.Within a few years, the country introduced rapid diagnostic tests and artemisinin-based combination therapy as part of the National Malaria Treatment Guidelines and began distributing free long-lasting insecticide treated nets to communities most at risk.In 2009, with support from the Global Fund to Fight AIDS, Tuberculosis and Malaria, Timor-Leste scaled up nationwide vector control efforts through the distribution of long-lasting insecticide-treated nets and indoor residual spraying. Malaria diagnosis was also expanded using microscopy and rapid diagnostic tests at the point of care across all local health posts.Facing the challenges of severe shortages of health workers and doctors, Timor-Leste made investments and developed its three-tier health system – comprising national hospitals, reference hospitals, community health centers (CHCs), and health posts – to ensure most residents can access care within an hour's walk. Additionally, citizens are provided with free health services at the point of care, as part of the government’s policy on free universal health care. Monthly mobile clinics and community outreach programmes further enhance health services in rural areas.Timor-Leste’s success in combating malaria highlights the importance of country leadership and strong collaboration between the Ministry of Health, WHO, local communities, non-governmental organizations, donors, and multiple government sectors. A real-time integrated case-based surveillance system ensures rapid data collection and response, while trained health workers ensure timely detection and screening of malaria cases, including at borders. These integrated efforts have paved the way for the country to be officially certified malaria-free."Timor-Leste’s malaria-free certification is a defining national triumph – driven by bold leadership, tireless efforts of health workers, and the resolve of its people. As a young nation, Timor-Leste stayed focused – testing, treating, and investigating swiftly. Ending transmission and maintaining zero deaths takes more than science; it takes grit. This victory protects generations, present and future, and shows what a determined country can achieve,” said Dr Arvind Mathur, WHO Representative to Timor-Leste. Note to the editorWHO malaria-free certificationThe final decision on awarding a malaria-free certification is made by the WHO Director-General, based on a recommendation by the Technical Advisory Group on Malaria Elimination and Certification and validation from the Malaria Policy Advisory Group. More on WHO’s malaria-free certification process. 

  • African Union and World Health Organization renew strategic partnership to drive impact and strengthen health systems in Africa
    on 05/24/2025 at 5:47 pm

    The World Health Organization (WHO) and the African Union (AU) Commission renewed their longstanding strategic partnership today with the signing of an updated Memorandum of Understanding (MoU) on the sidelines of the 78th World Health Assembly in Geneva. This renewed agreement reaffirms the joint commitment to advancing health security, universal health coverage, and sustainable development across the African continent at a time of unprecedented financial challenges in the global health landscape.It further underscores the African Union’s leadership in fostering collective action, inclusive partnerships, and regional resilience, and positions the Department of Health, Humanitarian Affairs, and Social Development of the AU Commission at the heart of the continent’s health policy implementation efforts.The agreement was signed by Her Excellency Ambassador Amma Adomaa Twum-Amoah, Commissioner for Health, Humanitarian Affairs and Social Development, on behalf of His Excellency Mahmoud Ali Youssouf, Chairperson of the African Union Commission, and Dr Tedros Adhanom Ghebreyesus, WHO Director-General. It marks a defining moment for primary health care and universal health coverage.Commissioner Twum-Amoah emphasized the strategic importance of the agreement and the AU’s leadership in shaping Africa’s health landscape:“This Agreement marks a new chapter in AU–WHO cooperation. By working together more closely, we can better respond to the health needs of our populations and ensure that no one is left behind. The African Union values WHO’s central and leading role in global health and looks forward to deepening this strategic partnership in support of our shared goals. We need to move from budgeting for survival to planning for health sovereignty,” she added.Building on the foundation of the 2019 MoU, the renewed agreement streamlines and strengthens collaboration across all AU entities. It aligns efforts in support of Africa’s health priorities and sets the stage for enhanced cooperation between WHO and the AU. It also reaffirms WHO’s central technical and normative leadership role in global and regional health, and its commitment to supporting the AU and its institutions in achieving health-related Sustainable Development Goals.“This renewed agreement comes at a critical time, as cuts to bilateral aid imperil the health of millions in Africa,” said Dr Tedros. “It reflects our determination to translate our partnership into tangible results for the people of Africa, and support countries to leave behind the era of aid dependency and transition to sustainable self-reliance. We are proud to stand with the African Union in driving forward the health priorities of the continent.”The Memorandum outlines five key areas of collaboration:health systems strengthening: including regulatory harmonization, support for local pharmaceutical manufacturing, traditional medicine, domestic health financing, workforce development, and digital health innovation;reproductive, maternal, neonatal, child, and adolescent health (RMNCAH): with continued support for the Campaign on Accelerated Reduction of Maternal Mortality in Africa (CARMMA Plus 2021–2030) and advancement of the reviewed Addis Ababa Declaration on Immunization (ADi);disease prevention and control: supporting the implementation of AU frameworks on communicable and noncommunicable diseases, including efforts to end AIDS, tuberculosis, and malaria; eliminate neglected tropical diseases (NTDs); and address the burden of viral hepatitis in line with WHO strategies;nutrition and food security: strengthening the nutrition agenda through implementation of the Africa Nutrition Strategy 2015–2025 and related WHO strategies; andhealth in emergency settings: by strengthening joint responses to humanitarian crises, conflicts, and climate-related emergencies.The timing of the renewed agreement is significant. It reflects the African Union’s elevated voice in global health governance – bolstered by its G20 membership – and highlights WHO’s ongoing key role as a trusted technical and operational partner.The renewed MoU marks new momentum for regional and multilateral cooperation to address Africa’s most pressing health challenges and deliver meaningful, lasting results on the continent.For further information:Professor Julio Rakotonirina | Director | Department of Health, Humanitarian Affairs and Social Development | African Union Commission | E-mail JulioR@africa-union.org   Ms Stéphanie Seydoux | Director | DG Envoy for Multilateral Affairs| World Health Organization| E-mail seydouxs@who.int 

  • Strengthening public health across Lebanon with EIB Global
    on 04/01/2025 at 11:55 am

    Dr Tedros Adhanom Ghebreyesus, Director-General of the World Health Organization (WHO), and Thomas Östros, Vice-President of the European Investment Bank (EIB Global), met at the EIB Group Forum in Luxembourg and signed an agreement for a €10 million grant to strengthen public health across Lebanon. The initiative will re-establish Lebanon's Central Public Health Laboratory and prioritize medication provision and healthcare support to over 50 000 people with chronic diseases like diabetes, cardiovascular issues, and cancer

Clinical Trials Watch

Search ClinicalTrials.gov by condition, intervention, and recruitment status. Confirm study details with the study team.

Antimicrobial Stewardship

Guidelines, resistance surveillance, and best practices.

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